Synthesis and Functional Evaluation of DNA-Assembled Polyamidoamine Dendrimer Clusters for Cancer Cell-Specific Targeting
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چکیده
منابع مشابه
Synthesis, cellular transport, and activity of polyamidoamine dendrimer-methylprednisolone conjugates.
Dendrimers have emerged as promising multifunctional nanomaterials for drug delivery due to their well-defined size and tailorability. We compare two schemes to obtain methylprednisolone (MP)-polyamidoamine dendrimer (PAMAM-G4-OH) conjugate. Glutaric acid (GA) was used as a spacer to facilitate the conjugation. In scheme A, PAMAM-G4-OH was first coupled to GA and then further conjugated with MP...
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ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 2005
ISSN: 1074-5521
DOI: 10.1016/j.chembiol.2004.10.016